Promescent

Promescent is a topical medication for the treatment of premature ejaculation. It is available over-the-counter in the U.S. by way of FDA Monograph 21CFR 348.10.

History

Promescent was invented in 2009 by Ronald F. Gilbert, former chief of the Department Of Urology at Hoag Hospital and assistant clinical professor of urology at UCI Medical School.

Urologists had been encouraged by the success of two topical anesthetics with fast absorption lidocaine/prilocaine eutectic formulations: EMLA and PSD502. However, neither of the products are approved by the FDA specifically for the treatment of PE due to prilocaine's unusual side effect of methemoglobinemia.

Technology

Gilbert sought a eutectic formulation with maximum absorption rate through the penile skin without the use of prilocaine. The U.S. Patent and Trademark Office has granted to Absorption Pharmaceuticals the following patents related to the technology of Promescent:

Patent No.

Date of Issue

Overview Description

8,507,561

13Aug2013

Formula application to premature ejaculation

8,563,616

22Oct2013

Composition of lidocaine-only eutectic formula

8,637,577

28Jan2014

Additional eutectic formulations

These patents protect novel lidocaine-only eutectic formulations which enable increased absorption of the anesthetic through the skin.

Cultural

Promescent has sparked numerous articles in the media AbOUT the increase awareness of premature ejaculation as the leading male [...] dysfunction and the effectiveness and practicality of various topical treatments. In October, 2013, Promescent was highlighted in a story on CNBC television and website entitled "Move over, Viagra. There's a new [...] [...] in town."

On February 25, 2014, Mr. Skin was on the Howard Stern SiriusXM radio show describing the benefits of Promescent. Mr. Skin said "...let's say you're 5 second guy, you'll become 5 minute guy; and if you're a 5 minute guy, you'll become a 25 minute guy." Upon which Howard exclaimed enthusiastically, "Wow! These guys are geniuses!"