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IMULAN BioTherapeutics, LLC, is a veterinary immunobiology company developing a range of immune based therapies for veterinary medicine. IMULAN BioTherapeutics, LLC has several divisions related to immuno-biology and comparative medicine.
IMULAN Clinical Trials, a clinical trial division of IMULAN BioTherapeutics, conducts a variety of comparative disease trials in oncology, asthma, sepsis, cardiology, and virology.
Technologies in Development
*TCR Vax: T-Cell receptor peptide vaccines - unique peptides with immune modulatory and immune regulatory properties. TCR Vax is undergoing development for canine atopic dermatitis and feline stomatitis.
*apSTAR Autologous patient specific tumor antigen response Cancer Laser: The apSTAR Veterinary Cancer Laser system is being developed for dogs, cats and horses with osteosarcoma, fibrosarcoma, melanoma, mastocytoma, and other solid tumor/cancer.
*Immune Selective Anti-Inflammatory Derivatives imsaids - small peptides which regulate granulocyte function, modulate neutrophil chemotaxis and activation, reduce the production of reactive oxygen species, and reduce the effects of endotoxin. Immune Selective Anti-Inflammatory Derivatives (ImSAIDs) are a class of peptides discovered to have diverse biological properties, including remarkable anti-inflammatory properties. ImSAIDs work by altering the activation and migration of inflammatory cells, which are immune cells responsible for amplifying the inflammatory response. The ImSAIDs represent a new category of anti-inflammatory and are unrelated to steroid hormones or non steroidal anti-inflammatories. The ImSAIDs were discovered by scientists evaluating biological properties of the submandibular gland and saliva. Early work in this area demonstrated that the submandibular gland released a host of factors which regulate systemic inflammatory responses and modulate systemic immune and inflammatory reactions. It is now well accepted that the immune, nervous and endocrine systems communicate and interact to control and modulate inflammation and tissue repair. One of the neuroendocrine pathways, when activated, results in the release of immune regulating peptides from the submandibular gland upon neuronal stimulation from sympathetic nerves. This pathway or communication is referred to as the cervical sympathetic trunk-submandibular gland (CST-SMG) axis, a regulatory system that plays a role in the systemic control of inflammation. Early work in identifying factors that played a role in the CST-SMG axis lead to the discovery of a seven amino acid peptide, called the submandibular gland peptide-T. SGP-T was demonstrated to have biological activity and thermoregulatory properties related to endotoxin exposure. SGP-T, an isolate of the submandibular gland, demonstrated its immunoregulatory properties and potential role in modulating the cervical sympathetic trunk-submandibular gland (CST-SMG) axis, and subsequently was shown to play an important role in the control of inflammation. One SGP-T derivative is a three amino acid sequence shown to be a potent anti-inflammatory molecule with systemic effects. This three amino acid peptide is phenylalanine-glutamine-glycine (FEG) and its D-isomeric form (feG), have become the foundation for the ImSAID category. Cellular Effects of feG: The cellular effects of the ImSAIDs are characterized in a number of publications. feG and related peptides are known to modulate leukocyte (white blood cells) activity by influencing cell surface receptors to inhibit excessive activation and tissue infiltration. One lead ImSAID, the tripeptide FEG (Phe-Glu-Gly) and its D-isomer feG are known to alter leukocyte adhesion involving actions on αMβ2 integrin, and inhibit the binding of CD16b (FCyRIII) antibody to human neutrophils. feG has also been shown to decrease circulating neutrophil and eosinophil accumulation, decrease intracellular oxidative activity and reduced the expression of CD49d after antigen exposure.
Company Partners
*AIM Therapeutics, Inc. - license agreements - (ImSAIDs anti-inflammatory platform)
*University of Arizona - license agreements
*ImmunoPhotonics, Inc. - license agreements (cancer laser)
Sources and notes
IMULAN website
* Medical News Today
* DVM Newsmagazine
* Veterinary Products News
* BioSpace - website
* Flinn Foundation website
* Arizona BioIndustry website

The Declaration on the Rights of Expelled or Deported Persons, developed by the Boston College Post-Deportation Human Rights Project, seeks to define basic procedural and substantive rights for persons who have been expelled by various coercive mechanisms. It describes the corresponding responsibilities of both sending and receiving states. Most significantly, the Declaration recognizes expelled or deported individuals as a cognizable legal class of people with specific, enforceable rights claims that go beyond current immigration laws in many countries. The drafters’ main goal is to inspire positive, pragmatic responses from nation-states, international bodies, NGO’s, and other concerned parties. The necessity of such a Declaration derives from the drafters’ concern that millions of expelled or deported individuals have faced a wide variety of often quite severe human rights abuses, including harsh treatment during deportation, loss of personal belongings and documents, lack of proper medical care, prolonged or permanent family separation, and severe social stigma. Many have been left with no recourse either in the country from which they have been removed or the country to which they have been sent.
Background
The Post-Deportation Human Rights Project, founded in 2006 by Professors Daniel Kanstroom, M. Brinton Lykes, Donald Hafner, and David Hollenbach, SJ at the Center for Human Rights and International Justice of Boston College, aims to conceptualize an entirely new area of law. The Project’s current staff attorney, Jessica Chicco, provides direct representation to individuals who have been deported. The Project promotes the rights of US deportees and their family members through research, policy analysis, human rights advocacy, and training programs. The ultimate aim of the Project is to advocate, in collaboration with affected families and communities, for fundamental changes that will introduce proportionality, compassion, and respect for family unity into US immigration laws and bring these laws into compliance with international human rights standards. The Declaration builds on the project's work to advance such fundamental notions as proportionality, family unity, and fairness into the deportation context.
Text of the Declaration
The current text of the Declaration (a work-in-progress) can be viewed here. It includes articles on general principles of nondiscrimination and protection for particularly vulnerable individuals, as well as provisions relating to travel and reception, reintegration, continued access to legal proceedings in the sending country, and respect for family unity.
Drafting Process
Two drafting conferences were hosted by the Boston College Post-Deportation Human Rights Project (PDHRP) relating to this Declaration. The first, in November 2012, was a roundtable with immigration and human rights experts and stakeholders to discuss the need and potential scope of the Declaration. In May 2014, the PDHRP, with support from the Clough Center, hosted a second major conference of scholars, activists, leaders of non-governmental organizations, and former government officials at the Connors Center in Dover, Massachusetts, to discuss the wisdom of the enterprise, and then to brainstorm how to improve upon—and to proceed towards publication and implementation of—the Declaration. Participants considered the moral, political, and legal bases upon which expelled people could claim enforceable rights, the content of those rights, and the obligations of “sending” and “receiving” states.
Additional Information
The Post-Deportation Human Rights Project will soon be launching a space to encourage people of all backgrounds - including scholars, researchers, individuals who have been personally affected by deportation - to comment, share information, exchange ideas, and brainstorm about next steps. Once the site has been created, a link will be available here.
Participants at Drafting Conferences
* Donald Anthonyson, Families for Freedom
* David Baluarte, Washington and Lee University, School of Law
* Seyla Benhabib, Yale University
* Jacqueline Bhabha, Harvard University
* Gabriel Camacho, American Friends Service Committee
* Jennifer Chacon, University of California - Irvine
* Jessica Chicco, Boston College - Center for Human Rights & International Justice
* Marlon Cifuentes, Olneyville Neighborhood Association
* Marla Conrad, Kino Border Initiative
* Nicholas De Genova, King’s College, London
* Katie Dingeman-Cerda, University of California - Irvine
* Matthew Gibney, University of Oxford
* Tanya Golash-Boza, University of California - Merced
* Michael Gordon, University of the West Indies - Jamaica
* Elspeth Guild, Radboud University of Nijmegen
* Barbara Harrell-Bond, Fahamu Refugee Programme
* Dina Haynes, New England School of Law
* Bernard Headley, University of the West Indies - Jamaica
* David Hollenbach, Boston College - Center for Human Rights & International Justice
* Mary Holper, Boston College Law School
* Kari Hong, Boston College Law School
* Daniel Kanstroom, Boston College Law School- Center for Human Rights & International Justice
* Michelle Karshan, Chans Altenativ
* Don Kerwin, Center for Migration Studies
* Tamar Lawrence-Samuel, Corporate Accountability International
* Arjen Leerkes, Erasmus University, Rotterdam
* Steve Legomsky, Washington University School of Law
* Hope Lewis, Northeastern University School of Law
* Brinton Lykes, Boston College - Center for Human Rights & International Justice
* David Martin, University of Virginia School of Law
* Ryan McManus, Hemenway & Barnes
* Grace Meng, Human Rights Watch
* Carlota Moctezuma, Immigration Advocates
* Melissa Moeinvaziri, University of Oxford
* Nancy Morawetz, New York University School of Law
* Hiroshi Motomura, UCLA School of Law
* Laura Murray-Tjan, Boston College Law School
* Serena Parekh, Northeastern University
* Wendy Ramirez, Kids in Need of Defense (KIND)
* Ronaldo Rauseo-Ricupero, Nixon Peabody LLC
* Trina Realmuto, National Immigration Project
* Christy Rodriguez, Ropes & Gray
* Rachel Rosenbloom, Northeastern University School of Law
* Rubén Rumbaut, University of California - Irvine
* Laura Schaefer, Benjamin Cardozo School of Law
* Telma Silva, Centre for Social Sciences of the University of the Azores
* Anita Sinha, American University Washington College of Law
* Serge Slama, Université Évry-Val d'Essonne
* Justine Stefanelli, Radboud University of Nijmegen
* Jacqueline Stevens, Northwestern University
* Juliet Stumpf, Lewis & Clark Law School

Richard Chanfray (Lyon, 1940 - Saint Tropez, July 14, 1983) was a French public figure in the 1970s. He claimed to be the Comte de Saint-Germain and appeared in numerous European television shows claiming to transmute lead into gold.
Biography
Richard Chanfray's magic career started in 1973 in a Parisian theater, where he was announced as "the man who transmutes lead into gold". This alchemical act was supposedly performed without tricks.
He was born on 4 April 1940 in the French city of Lyon. His childhood was spent on the streets and he became a thief. Arrested for assaulting a woman during a robbery and sentenced to six years, he read some antique books in prison, and learned about the Comte de Saint-Germain, a mysterious alchemist, who claimed to be capable of transmutating lead into gold, brewing potions, and acquiring immortality. Chanfray adopted that personality, using French high society's fondness for magic, esoterism and hermeticism. He quickly became rich and well-known through his exploits, for example giving divinations and psychic readings to various famous people as well as through his outlandish claims.
In 1972 he met the singer Dalida, at the height of her fame. Her husband, Lucien Morisse, and her lover, Luigi Tenco, had both previously committed suicide. When Dalida met Chanfray, she quickly became infatuated. She recognized his paranoia, however: he slept with a shotgun under his bed. He also spent another year in prison, as well as being forced to pay FF restitution, when he shot a man whom he found naked in his kitchen late one night. The man was only superficially wounded, and turned out to be the servant's lover.
The incident marked the start of his decline. The couple ran out of money and Chanfray attempted music, painting, and sculpture, all without success. Dalida and Chanfray separated, but despite his problems, he continued to be a part of the celebrity society of Paris and Saint Tropez. He became the lover of the Trintignan "baroness", Paula de Loos, whose title was as false as his own. De Loos was, however, allegedly a millionaire and when Chanfray began to suspect the activities of de Loos's financial administrator, he threatened him with a rifle. He was again imprisoned and fined—to which he looked to de Loos for help. She, however, was also heavily in debt.
He last appeared in public at a party in Saint Tropez, in June 1983. He was reportedly very thin, with white hair and an exhausted appearance.
On the 14th of July 1983, in a town near Saint Tropez, Chanfray and de Loos committed suicide, ingesting barbiturates while inhaling the exhaust of his car. Nearby was a suicide note that read: "I leave and I bring her with me, because she is so like me..."
Self-claimed powers
Richard Chanfray claimed to have many powers, most of them related to alchemy. He also claimed on numerous occasions that his knowledge came from a "mysterious man" whom he had met in his past. He swore to never reveal said person's identity.
Some of the powers Chanfray's claimed to possess:
*Transmutation of lead into gold. Chanfray performed this trick several times in public, and some European television stations recorded him allegedly transmutating the metals. Stage magicians, scientists and jewellers were invited to some of his soirées, and none apparently discovered the trick.
*The power of immortality. Traditional alchemy considered those two powers (transmutation and immortality) to go hand-in-hand. A Spanish reporter, José María Íñigo, was once invited to Chanfray's house. According to Íñigo "he threw a bit of this powder over a dog's corpse. After a few spasmodic movements, the dog arose and walked a few steps before falling again and remaining dead". It is unclear whether the dog was actually dead before, or even after, the trick.
*The capability of remembering past lives. When invited to old palaces or castles, he claimed to have been there before, in a past life. He would demonstrate this by identifying private areas of the building, secret passages, and so on. It has been suggested that Chanfray studied the blueprints of the buildings, open to the public, before going to these places.